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Swollen lymph nodes are often an unpleasant symptom. But experts say that when these clusters of cells are tender and painful, it’s often a sign your immune system is doing its job. Ahead, we’ll explain common causes of swollen lymph nodes.

“Lymph nodes represent the main factory for the immune system—that’s where all of the activity occurs that relates to the generation of antibodies and the mobilization of cells to fight off infection,” says Stanley Rockson, M.D. , founding director of the Stanford Center for Lymphatic and Venous Disorders and professor of lymphatic research and medicine at Stanford Health Care. “They reflect the…

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